IL-4-Independent Inhibition of IL-12 Responsiveness DuringLeishmania amazonensisInfection
نویسندگان
چکیده
منابع مشابه
IL-4-independent inhibition of IL-12 responsiveness during Leishmania amazonensis infection.
Leishmania amazonensis induces a nonhealing infection in C3H mice, whereas infection with Leishmania major is self-healing. We found that C3H mice infected with L. amazonensis exhibited decreased IL-12 production, which could account for the susceptibility to this organism. However, exogenous IL-12 administration failed to induce a healing immune response. The failure of L. amazonensis-infected...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2000
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.165.1.364